formulation of nicotine buccal adhesive control release tablet for nicotine replacement therapy

preparation and evaluation of nicotine slow release mucoadhesive film for nicotine replacement therapy

Inhaled nicotine replacement therapy

There are a large number of smokers who want to quit smoking but have failed in their attempts to do so, with many having been unsuccessful at quitting multiple times over their lifetime. The existing marketed nicotine replacement therapies (NRT) have only marginal effectiveness and none provide a comparable physiological response to that derived from cigarette smoking; that is, rapid absorptio...

Nicotine replacement therapy.

OBJECTIVE To review the literature on nicotine dependence, nicotine pharmacology, health consequences associated with the use of nicotine, and nicotine replacement therapies used to aid smokers who are nicotine dependent. DATA SOURCES A review of articles, book bibliographies, and published studies identified by a search of the MEDLINE database from 1982 to 1996 on nicotine dependence, nicoti...

Cardiovascular toxicity of nicotine: implications for nicotine replacement therapy.

This review discusses the known cardiovascular effects of smoking and the effects of nicotine without tobacco smoke and interprets the available data on cardiovascular risk during nicotine replacement therapy (NRT). Nicotine gum and patches are now approved for over the counter sale in the United States. Smokers with cardiovascular disease are advised to seek physician counseling before using n...

Nicotine replacement therapy in pregnancy.

Cigarette smoking is a major modifiable cause of adverse pregnancy outcomes. Nicotine-replacement therapy (NRT) is recommended in guidelines, but its efficacy and safety during pregnancy is uncertain. This multicentre double-blind trial recruited 1050 pregnant participants who were in their 12–24 weeks’ gestation periods. All of them smoked ≥5 cigarettes per day (median 20). Participants were r...

[Nicotine replacement therapy during pregnancy].

In spite of the fact that smoking is the main cause of obstetric morbidity and mortality, 20% of North American women smoke during pregnancy. In Spain, this figure is as high as 30% to 35%. Treating smoking addiction in these patients should be the first and most important therapeutic measure undertaken by health professionals responsible for the care of pregnant women. All experts recommend th...